siv vaccines การใช้

• In the study, newborns received the SIV vaccine by oral dosing shortly after birth.
• Apparently, even a weakened SIV vaccine can mutate into disease-causing forms, Ruprecht said.
• But studies on monkey newborns, Ruprecht said, show that the modified SIV vaccine itself turns into a killer.
• Of the 97 recent H3N2 isolates examined, only 41 had strong serologic cross-reactions with antiserum to three commercial SIV vaccines.
• NIAID-funded SIV research has shown that challenging monkeys with a cytomegalovirus ( CMV )-based SIV vaccine results in containment of virus.
• Many experts had looked to this SIV vaccine as the best model for developing a human counterpart, because it seemed to provide the strongest evidence of protection against an AIDS-like virus.
• In 1993 Dr . Ruprecht began her experiments by injecting nine newborn monkeys with the weakened SIV vaccine developed by Dr . Ronald Desrosiers of the New England Primate Center in Southboro, Mass.
• Andino and his colleagues will soon begin testing a polio-based SIV vaccine at University of California at Davis to learn whether it can protect the monkeys against infection from the monkey virus and thereby prevent them from developing full-blown simian AIDS.
• Most H3N2 virus isolates are triple reassortants, containing genes from human ( HA, NA, and PB1 ), swine ( NS, NP, and M ), and swine farms typically include the use of one of several bivalent SIV vaccines commercially available in the United States.